Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kdr  kinase insert domain protein receptor   (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2)
Results	Reference
1	J:32219 Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A, Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 1996 Apr 4;380(6573):435-9
1	J:60758 Drake CJ, Fleming PA, Vasculogenesis in the day 6.5 to 9.5 mouse embryo. Blood. 2000 Mar 1;95(5):1671-9
1	J:140543 Ema M, Yokomizo T, Wakamatsu A, Terunuma T, Yamamoto M, Takahashi S, Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo. Blood. 2006 Dec 15;108(13):4018-24
1*	J:84599 Ferkowicz MJ, Starr M, Xie X, Li W, Johnson SA, Shelley WC, Morrison PR, Yoder MC, CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development. 2003 Sep;130(18):4393-403
1	J:224939 Hare LM, Schwarz Q, Wiszniak S, Gurung R, Montgomery KG, Mitchell CA, Phillips WA, Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects. Dev Biol. 2015 Aug 1;404(1):14-26
1*	J:87043 Huang C, Sheikh F, Hollander M, Cai C, Becker D, Chu PH, Evans S, Chen J, Embryonic atrial function is essential for mouse embryogenesis, cardiac morphogenesis and angiogenesis. Development. 2003 Dec;130(24):6111-9
1	J:189368 Kamijo H, Matsumura Y, Thumkeo D, Koike S, Masu M, Shimizu Y, Ishizaki T, Narumiya S, Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II. Genes Cells. 2011 Oct;16(10):1012-21
1	J:214903 Kataoka H, Hayashi M, Kobayashi K, Ding G, Tanaka Y, Nishikawa S, Region-specific Etv2 ablation revealed the critical origin of hemogenic capacity from Hox6-positive caudal-lateral primitive mesoderm. Exp Hematol. 2013 Jun;41(6):567-581.e9
1	J:155850 Lee D, Park C, Lee H, Lugus JJ, Kim SH, Arentson E, Chung YS, Gomez G, Kyba M, Lin S, Janknecht R, Lim DS, Choi K, ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell. 2008 May 8;2(5):497-507
1*	J:75316 Liao HJ, Kume T, McKay C, Xu MJ, Ihle JN, Carpenter G, Absence of Erythrogenesis and Vasculogenesis in Plcg1-deficient Mice. J Biol Chem. 2002 Mar 15;277(11):9335-41
1	J:85043 Otto DM, Henderson CJ, Carrie D, Davey M, Gundersen TE, Blomhoff R, Adams RH, Tickle C, Wolf CR, Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis. Mol Cell Biol. 2003 Sep;23(17):6103-16
1	J:266578 Plein A, Fantin A, Denti L, Pollard JW, Ruhrberg C, Erythro-myeloid progenitors contribute endothelial cells to blood vessels. Nature. 2018 Oct;562(7726):223-228
1	J:96124 Sakurai Y, Ohgimoto K, Kataoka Y, Yoshida N, Shibuya M, Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice. Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1076-81
1*	J:262744 Shetty R, Joshi D, Jain M, Vasudevan M, Paul JC, Bhat G, Banerjee P, Abe T, Kiyonari H, VijayRaghavan K, Inamdar MS, Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning. Sci Rep. 2018 Apr 4;8(1):5632
1	J:203698 Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Maziere A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W, Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood. 2013 Nov 21;122(22):3678-90